Case Report| Volume 19, ISSUE 4, 104563, April 2023

Congenital Cytomegalovirus Infection

Published:February 21, 2023DOI:


      • Congenital cytomegalovirus (CMV) is the most common congenital infection and the leading cause of nongenetic sensorineural hearing loss in children.
      • Congenital CMV is associated with cognitive deficits, developmental delays, and sensorineural hearing loss, but recognition is often delayed by parents and providers.
      • A case of congenital CMV infection resulting in neurodevelopmental delays and sensorineural hearing loss is presented.


      Congenital cytomegalovirus (CMV) infection is the most common intrauterine infection and is the leading nongenetic cause of sensorineural hearing loss and neurodevelopmental delays in the pediatric population. Despite its high prevalence and significant sequelae, congenital CMV in the pregnant woman and neonate often goes undiagnosed. We present the case of a 23-month-old child presenting with developmental delays and bilateral sensorineural hearing loss as a result of CMV and describe with this case report the clinical features, diagnosis, testing, management, and prognosis of congenital CMV.


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      Michelle P. Zappas, DNP, FNP-BC is a clinical associate professor in the Department of Nursing at the Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, and can be contacted at [email protected]


      Sharon P. O'Neill, DNP, JD, FNP-BC, PMHNP-BC, is a clinical associate professor at the New York University Rory Meyers College of Nursing, New York.


      Courtney Rotz, MSN, FNP-BC, is an adjunct professor in the Department of Nursing at the Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles.