Highlights
- •Repetitive transcranial magnetic stimulation (rTMS) has beneficial effects on depression and cognitive performance in patients with postpartum depression (PPD).
- •Curative effects of rTMS attributable to distinctive parameters are observed for PPD patients.
- •The optimal stimulation protocols of rTMS for PPD have initially been ascertained.
Abstract
The purpose of this meta-analysis is to evaluate the beneficial effects and ascertain
the optimal stimulation protocol of repetitive transcranial magnetic stimulation (rTMS)
on patients with postpartum depression (PPD). We performed a comprehensive literature
search for randomized clinical trials through September 2022. On the basis of the
inclusion criteria, 23 studies were selected for the analysis. The results of our
meta-analysis showed that rTMS produced significant effects. Among the studies included
in the meta-analysis, the scales used to measure PPD in the participants included
the Hamilton Depression Scale (standardized mean differences [SMD] = −0.90; P < 0.05), Edinburgh Postnatal Depression Scale (SMD = −1.05; P < 0.05), Mini-Mental State Examination (SMD = 2.88; P < 0.05), and quality-of-life scores (SMD = 1.81; P < 0.05). Furthermore, rTMS was found to exert a beneficial effect on depression and
cognitive performance in PPD patients with distinct optimal stimulation parameters.
Keywords
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Biography
Tao Wang, MS, Physician, People’s Hospital of Leshan, Leshan, China and can be contacted at [email protected] Hongxia Wu, MS, Physician, Department of Radiology, Hospital of Traditional Chinese Medicine of Leshan, Leshan, China.
Biography
Yi Jiang, MD, Senior associate consult, National Clinical Research Center for Geriatrics, The West China Hospital of Sichuan University, Chengdu, China.
Biography
Wei Huang, MS, Attending Physician, Dong Yu, MD, Chief Physician, and Xiao Zhang, MS, Chief Physician, Department of Radiology, People’s Hospital of Leshan, Leshan, China.
Biography
Qiwen Mu, MD, PhD, Professor and senior consult, Institute of Rehabilitation and Imaging of Brain Function, Nanchong Central Hospital, Nanchong, China, and Department of Radiology, Peking University Third Hospital, Beijing, China.
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Published online: December 01, 2022
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In compliance with standard ethical guidelines, the authors report no relationships with business or industry that would pose a conflict of interest.
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