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Case Challenge|Articles in Press, 104456

Acute Genital Ulcers: When the Etiology Is Beyond the Obvious

      Highlights

      • There are multiple etiologic factors the primary provider must consider when delivering care for the patient with genital ulcers.
      • Differentials will include sexually transmitted infection (STI) or venereal origins, especially herpes simplex virus I or II, which should be among the first differential diagnoses one considers.
      • Clinicians need to be aware of other rare, but possible, etiologic factors for this extremely painful and debilitating illness.
      • The diagnosis of nonsexually acquired genital ulcers is dependent on the art of exclusion and requires thorough history, physical examination, and diagnostic laboratory testing in confirming the diagnosis.
      • Additionally, the clinician must realize that patients and significant others may be very confused and concerned about the presenting symptoms that mimic STI-related symptoms, which may cause psychological stress, especially in the adolescent patient.

      Abstract

      This case study challenge describes the case of a 13-year-old female who presented to a primary care clinic with extremely painful vaginal lesions. She also had generalized symptoms such as fatigue, malaise, and low-grade fever. An adolescent with these presenting symptoms may make the nurse practitioner immediately consider the common sexually transmitted diseases often presented at primary and urgent care settings, yet there are many differentials that should be considered. Despite what might seem obvious, a thorough history, physical examination, and diagnostic testing are imperative to avoid misdiagnosis.

      Keywords

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      Biography

      Daisy G. Mullassery, DrNP, WHNP-BC, is a Assistant Professor-Clinical at the University of Texas Health Science Center Cizik School of Nursing in Houston and can be contacted at [email protected]

      Biography

      Rebecca Tsusaki, PhD, WHNP-BC, is a Assistant Professor-Clinical at the University of Texas Health Science Center Cizik School of Nursing.