Hereditary Angioedema Management: Individualization

Published:November 01, 2021DOI:


      • The key aim of hereditary angioedema (HAE) management is to improve quality of life.
      • HAE management plans are individualized to patients’ lifestyles and preferences.
      • Shared decision making is used to facilitate individualization of HAE management.
      • Nurse practitioners are key to successful treatment individualization in HAE.


      Hereditary angioedema (HAE) is a chronic, incurable disease characterized by recurrent, unpredictable episodes of swelling in various parts of the body. The presentation of HAE is highly variable, and multiple treatment options are available for disease control and prophylaxis. HAE management plans should therefore be individualized to reduce mortality and morbidity in a way that prioritizes quality of life based on each patient’s lifestyle, preferences, and goals. This report discusses the key considerations in HAE management and patient-centered care, including the use of shared decision making and the vital roles performed by nurse practitioners and other health care providers.


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      Kristin Epland, MSP, FNP-C, Advancements in Allergy and Asthma Care, Minnetonka, MN, and can be contacted at [email protected]


      Melanie Wayne, MSN, FNP-BC, Oregon Allergy Associates, Eugene, OR.


      Heather Pein, PA-C, IMMUNOe Research, Centennial, CO. Kristin Epland is a nurse consultant with Takeda.