The Journal for Nurse Practitioners
Volume 4, Issue 6 , Pages 439-444 , June 2008

Cardiovascular Effects of Sleep Apnea

  • Katherine J. Dodson

      Affiliations

    • Katherine J. Dodson, RN, MN, FNP-C, works as a Family Nurse Practitioner for Clackamas Community Health in Oregon City, OR.

References 

  1. Kline LR . Clinical presentation and diagnosis of obstructive sleep apnea-hypopnea in adults. UpToDate . Available at: www.uptodate.com March 8, 2007; Accessed July 15, 2007.
  2. Institute for Clinical Systems Improvement [ICSI]. Brief summary: diagnosis and treatment of obstructive sleep apnea in adults. National Guideline Clearinghouse. March 2007. Available at: http://guideline.gov/summary/summary.aspx?doc_id=10809&nbr=005634&string=obstructive+AND+sleep+AND+apnea. Accessed August 31, 2007.
  3. Parrish JM , Somers VK . Obstructive sleep apnea and cardiovascular disease . Mayo Clin Proc . 2004;79(8):1036–1046
  4. Young T , Peppard PE , Gottlieb DJ . Epidemiology of sleep apnea . Am J Respir Crit Care Med . 2002;165:1217–1239
  5. Shamsuzzaman AS , Gersh BJ , Somers VK . Obstructive sleep apnea: implications for cardiac and vascular disease . JAMA . 2003;290(14):1906–1914
  6. Young T , Skatrud J , Peppard PE . Risk factors for obstructive sleep apnea . JAMA . 2004;291(16):2013–2016
  7. Ancoli-Israe S , Klauber M , Stepanowski C , et al.   Sleep-disordered breathing in African-American elderly . Am J Respir Crit Care Med . 1995;152:1946–1949
  8. Redline S . Epidemiology of sleep-disordered breathing . Semin Respir Crit Care Med . 1998;19:113–122
  9. Peppard PE , Young T , Palta M . Longitudinal study of moderate weight change and sleep-disordered breathing . JAMA . 2000;284:3015–3021
  10. Newman AB , Nieto FJ , Guidry U , et al.   Relation of sleep-disordered breathing to cardiovascular risk factors: the Sleep Heart Heath Study . Am J Epidemiol . 2001;154(1):50–59
  11. Young T , Shahar E , Nieto F , et al.   Predictors of sleep-disordered breathing in community-dwelling adults . Arch Intern Med . 2002;162:893–900
  12. Einhorn D , Erman M , Philis-Tsimkas A , et al.   Prevalence and associations of sleep apnea in a population of adults with type 2 Diabetes Mellitus . Diabetes . 2005;54:A582
  13. Schwab RJ , Pasirstein M , Kaplan L , et al.   Family aggregation of upper airway soft tissue structures in normal subjects and patients with sleep apnea . Am J Respir Crit Care Med . 2006;173(4):453–463
  14. Zhang L , Samet J , Caffo B , et al.   Cigarette smoking and nocturnal sleep architecture . Am J Epidemiol . 2006;164(6):529–537
  15. Young T , Finn L , Austin D , et al.   Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study . Am J Respir Crit Care Med . 2003;167:1181–1185
  16. Bixler EO , Vgontzas AN , Have TT . Prevalence of sleep disordered breathing in women: effects of gender . Am J Respir Crit Care Med . 1998;157:144–148
  17. Rappai M , Collop N , Kemp S , et al.   The nose and sleep-disordered breathing: what we know and what we do not know . Chest . 2003;124(6):2039–2054
  18. El-Ad B , Lavie P . Effect of sleep apnea on cognition and mood . Int Rev Psychiatry . 2005;17(4):277–282
  19. Fletcher EC . Sympathetic over activity in the etiology of hypertension of obstuctive sleep apnea . Sleep . 2003;26(1):15–19
  20. Bokinsky G , Miller M , Ault K , et al.   Spontaneous platelet activation and aggregation during obstructive sleep and apnea and its response to therapy with nasal continuous positive airway pressure: a preliminary investigation . Chest . 1995;108:625–630
  21. Hoffstein V , Herridge M , Mateika S , et al.   Hematocrit levels in sleep apnea . Chest . 1994;106:787–791
  22. Chin K , Ohi M , Keta H . Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome . Am J Respir Crit Care Med . 1996;153:1972–1976
  23. Nobili L , Schiavi G , Bonzano E . Morning increase in whole blood viscosity in obstructive sleep apnea syndrome . Clin Hemorheol Microcirculation . 2000;22:21–27
  24. McArdle N , Hillman D , Beilin L , et al.   Metabolic risk factors for vascular disease in obstructive sleep apnea: a matched controlled study . Am J Respir Crit Care Med . 2007;175(2):190–196
  25. Marin JM , Carrizo SJ , Vincente E , et al.   Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopneoea with or without treatment with continuous positive airway pressure: an observational study . Lancet . 2005;365(9464):1046–1053
  26. Peppard PE , Young T , Palta M , et al.   Prospective study of the association between sleep-disordered breathing and hypertension . N Engl J Med . 2000;342:1378–1384
  27. Haentjens P , Van Meerhaeghe A , Moscariello A , et al.   The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea . Arch Intern Med . 2007;167:757–765
  28. Hla KM , Skatrud JB , Finn L , et al.   The effect of correction of sleep-disordered breathing on BP and untreated hypertension . Chest . 2002;122:1125–1132
  29. Caples SM , Garcia-Touchard A , Somers VK . Sleep-disordered breathing and cardiovascular risk . Sleep . 2007;30(3):291–304
  30. Mehra R , Benjamin EJ , Shahar E . Association of nocturnal arrhythmias with sleep disordered breathing: the Sleep Heart Health Study . Am J Respir Crit Care Med . 2006;173:910–916
  31. Alonzo-Fernandez A , Garcia-Rio F , Racionero MA . Cardiac rhythm disturbances and ST-segment depression episodes in patients with obstructive sleep apnea-hypoapnea syndrome and its mechanisms . Chest . 2005;127:15–22
  32. University of Texas, School of Nursing, Family Nurse Practitioner Program. Screening for obstructive sleep apnea in the primary care setting. National Guideline Clearinghouse . Available at: http://guideline.gov/summary/summary.aspx?doc_id=9436&nbr=005057&string=Screening+AND+obstructive+AND+sleep+AND+apnea May 2006; Accessed August 31, 2007.
  33. Becker HF , Jerrentrup A , Ploch T , et al.   Effects of nasal continuous positive airway pressure treatment and blood pressure in patients with obstructive sleep apnea . Circulation . 2003;107:68–73
  34. Weaver T . Compliance with continuous positive airway pressure (CPAP). UptoDate . Available at: http://utdol.com/utd/topic.do?topicKey=sleepdis/6186&view=text 2007; Accessed July 30, 2007.
  35. Morgenthaler TI , Kapen S , Lee-Chiong T , et al.   Practice parameters for the medical therapy of obstructive sleep apnea . Sleep . 2006;29(8):1031–1035

 In conjunction with national ethical standards, the author reports no relationships with business or industry that represent a conflict of interest.

PII: S1555-4155(08)00093-7

doi: 10.1016/j.nurpra.2008.02.017

The Journal for Nurse Practitioners
Volume 4, Issue 6 , Pages 439-444 , June 2008

Article Tools